{"id":3285,"date":"2021-06-03T18:10:03","date_gmt":"2021-06-03T18:10:03","guid":{"rendered":"https:\/\/stuarttherapeutics.com\/?page_id=3285"},"modified":"2021-09-15T20:22:14","modified_gmt":"2021-09-15T20:22:14","slug":"dry-amd","status":"publish","type":"page","link":"https:\/\/stuarttherapeutics.com\/dry-amd\/","title":{"rendered":"Dry\/Wet AMD"},"content":{"rendered":"

Dry Age Related Macular Degeneration<\/span><\/h4>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section>
<\/div>
Dry age-related macular degeneration (Dry AMD) results in the deterioration of the tissues at the back of the eye, in the retina. This deterioration causes loss of retinal pigment epithelial cells and associated portions of the photoreceptor layer.<\/span><\/h5>\n<\/div>
<\/div>
<\/div><\/div><\/div><\/div><\/div><\/div>
<\/div>
\"https:\/\/stuarttherapeutics.com\/wp-content\/uploads\/Dry-Wet-AMD-LR2.png\"<\/span><\/div>
<\/div>
<\/div><\/div><\/div><\/div>

This phenomenon leads to a thinning and drying out of the macula, causing the macula to lose its function. The amount of central vision loss is directly related to the location and amount of retinal thinning caused by the drusen.\u00a0 The thinning and drying out of the macula results in deterioration of the retinal pigment epithelial cells and underlying Bruch\u2019s membrane and choriocapillaris, both of which have collagen in their structure.<\/p>\n<\/div>

<\/div><\/div><\/div><\/div><\/div><\/div>
<\/div>
\"https:\/\/stuarttherapeutics.com\/wp-content\/uploads\/Dry-Wet-AMD-LR2-Wet.png\"<\/span><\/div>
<\/div><\/div><\/div><\/div>

Dry AMD is a slow acting disease whose causes are not fully understood. The characteristic damage cycle associated with Dry AMD includes disruption of Bruch\u2019s membrane at the back of the eye, which is the collagen layer that supports the important retinal pigment epithelial (RPE)cells. Disruption in Bruch\u2019s results eventually in cell death in the RPE layer, which is followed by atrophy of the photoreceptor layer. Deposits known as drusen can form within Bruch\u2019s membrane, or in the RPE layer itself, and appear to contribute to the disruption.<\/p>\n<\/div>

<\/div><\/div><\/div><\/div><\/div><\/div>
<\/div><\/div><\/div><\/div><\/div><\/section>
<\/div><\/div><\/div>
<\/div>
STUART THERAPEUTICS<\/span><\/h6>\n<\/div>

Our Approach<\/span><\/a><\/h4>\n<\/div>

For Dry AMD, a PolyCol variant administered via drop formulation penetrates through the inner limiting membrane, and, acts to rapidly repair damage to Bruch\u2019s membrane, providing a healthy environment for retinal pigment epithelial cell proliferation and adherence.<\/p>\n<\/div>

<\/div><\/div><\/div><\/div>
<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":4085,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_mi_skip_tracking":false},"_links":{"self":[{"href":"https:\/\/stuarttherapeutics.com\/wp-json\/wp\/v2\/pages\/3285"}],"collection":[{"href":"https:\/\/stuarttherapeutics.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/stuarttherapeutics.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/stuarttherapeutics.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/stuarttherapeutics.com\/wp-json\/wp\/v2\/comments?post=3285"}],"version-history":[{"count":0,"href":"https:\/\/stuarttherapeutics.com\/wp-json\/wp\/v2\/pages\/3285\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/stuarttherapeutics.com\/wp-json\/wp\/v2\/media\/4085"}],"wp:attachment":[{"href":"https:\/\/stuarttherapeutics.com\/wp-json\/wp\/v2\/media?parent=3285"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}